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A novel data gathering approach that relies on “text mining” can help process developers better understand the complex relationships between culture conditions and glycosylation, say the authors of new research.
A protein’s glycosylation profile—the pattern of glycan residues that bind to the core molecule during production—dictates its therapeutic function and efficacy. A reproducible profile is key to achieving quality and consistency goals.
And, for the most part, biopharma is good at using experimentation to…