Bioinformatics

Integration of public datasets into one atlas We collected all publicly available single-cell datasets of plaque from carotid, coronary and femoral arteries covering a total of …

Understanding how cells are arranged in tissues is just as important as knowing what genes they are expressing. Traditional single-cell and single-nucleus RNA sequencing has given …

By Bio-IT World Staff   August 28, 2025 | Ultima Genomics unveiled updates on the single-nucleotide variant (SNV) detection capabilities of its plus-minus sequencing (ppmSeq) technology, which …

A comprehensive MR analysis was performed on 139 eQTLs linked to anti-allergic drugs within discovery cohorts of 122,733 CAD patients, 68,157 HF patients, 395,795 MI patients, …

When cells expire, they leave behind an activity log of sorts: RNA expelled into blood plasma that reveal changes in gene expression, cellular signaling, tissue injury …

By Eugene Gerden  August 7, 2025 | Russia plans to significantly expand its national database of genetic information by 2030 according to a recent decree approved …

Plasma cells subsequently discharge specific antibodies (Abs) into the circulation, which gradually enter other body fluids. dependent on precise antigen recognition and Cd44 MHC class I …

Let \({\textbf{Y}}_{j}\in {\mathbb {R}}^{n_j\times p}\) denote gene expression for \(n_j\) cells and p genes in group/donor \(j=1,\dots , J\) and let \({\textbf{X}}_j\in {\mathbb {R}}^{n_j\times 2}\) denote …

Single-cell RNA sequencing (scRNA-seq) has changed the way researchers study cells by allowing them to examine gene expression at the level of individual cells. This technology …

By Bio-IT World Staff July 10, 2025 | David Hewlett, renowned for portraying Dr. Rodney McKay in the Stargate franchise, recently joined Trends from the Trenches …